A facile approach to enhance antigen response for personalized cancer vaccination published in Nature Materials

March 22, 2018
Congrats to Aileen and team on their recent publication which looked at using polyethyleneimine (PEI) in mesoporous silica rod (MSR) vaccines to enhance antigen immunogenicity. The MSR-PEI vaccine substantially improved therapeutic outcomes in three challenging tumor models while enabling the presentation of large sets of neoantigens and synergizing with checkpoint blockade therapy. Check out their work here: A facile approach to enhance antigen response for personalized cancer vaccination.