News

Dr. Meadhbh Brennan starts faculty position at the National University of Ireland Galway (NUIG)

June 9, 2020
A big congrats to Meadhbh, who was recently awarded the prestigious ERC starting grant, on her faculty position at the National University of Ireland Galway (NUIG) in a joint appointment between Medicine and Bioengineering. Her positive energy and important contributions will be greatly missed! We can't wait to hear about your future work and success! Read more about Dr. Meadhbh Brennan starts faculty position at the National University of Ireland Galway (NUIG)

A biomaterial-based vaccine eliciting durable tumour-specific responses against acute myeloid leukaemia published in Nature Biomedical Engineering

January 4, 2020

Congrats to Nisarg, Alex and team on their recent publication which describes a macroporous-biomaterial vaccine for the treatment of acute myeloid lymphoma (AML). The AML vaccine prevented the engraftment of tumor cells when administered as a prophylactic and in...

Read more about A biomaterial-based vaccine eliciting durable tumour-specific responses against acute myeloid leukaemia published in Nature Biomedical Engineering

Clickable, acid labile immunosuppressive prodrugs for in vivo targeting published in Biomaterial Science

January 1, 2020

Congrats to Hua and team on their recent publication which describes DBCO-modified prodrugs of various immunosuppressive drugs and their targeted conjugation to azido-modified hydrogels via Click chemistry. Placement of these hydrogels in tissues facilitates sustained, local release of drugs and enables repeatable refilling via systemic administration of acid-labile prodrugs after drug...

Read more about Clickable, acid labile immunosuppressive prodrugs for in vivo targeting published in Biomaterial Science

Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation published in PNAS

July 30, 2019
Congrats to Angelo and team on their recent publication which describes a microfluidic-based biomaterial encapsulation approach to improve the in vivo residence time of intravenously delivered MSCs - these modifications extended cell persistence even in the presence of innate and adaptive immunity-mediated clearance. Check it out here: ... Read more about Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation published in PNAS

Bioinspired mechanically active adhesive dressings to accelerate wound closure published in Science Advances

July 24, 2019
Congrats to Serena, Jianyu, and team on their recent publication which describes a novel wound dressing that combines high stretchability, toughness, tissue adhesion, and antimicrobial function to actively contract and seal wounds. Check it out here: Bioinspired mechanically... Read more about Bioinspired mechanically active adhesive dressings to accelerate wound closure published in Science Advances