News

2018_summer_undergrads

Mooney lab summer students present research

August 4, 2018

Congrats to all Mooney lab undergraduates on a productive summer! Great to see such a wide breadth of projects ranging from cell biology to hydrogel mechanics.

Pictured from left: Calvin Marambo, Ege Eskibozkurt, Justine Keth, Luna Nadja Maldonado, Nikko Jeffries, Darnell Cuylear, Soore Oguntuyo, Anna Vaynrub, Evan Thompson

PLGA scaffold

Biomaterial scaffold-based immunotherapy platforms licensed to Novartis

March 31, 2018

The Wyss Institute at Harvard Universtiy and Dana-Farber Cancer Institute have entered a licensing and collaboration agreement with Novartis to develop our biomaterial systems to delivery next generation immunotherapies. Our approach uses an injectable or implantable biomaterial scaffold that recruits and trains the body's endogenous immune cells to identify and kill a patient's own cancerous cells. A big congratulations to Dave...

Read more about Biomaterial scaffold-based immunotherapy platforms licensed to Novartis

A facile approach to enhance antigen response for personalized cancer vaccination published in Nature Materials

March 22, 2018
Congrats to Aileen and team on their recent publication which looked at using polyethyleneimine (PEI) in mesoporous silica rod (MSR) vaccines to enhance antigen immunogenicity. The MSR-PEI vaccine substantially improved therapeutic outcomes in three challenging tumor models while enabling the presentation of large sets of neoantigens and synergizing with checkpoint blockade therapy. Check out their work here: ... Read more about A facile approach to enhance antigen response for personalized cancer vaccination published in Nature Materials

Injectable, Tough Alginate Cryogels as Cancer Vaccines and Tough Composite Hydrogels with High Loading and Local Release of Biological Drugs published in Advanced Healthcare Materials

March 15, 2018

Congrats to Ting and Jianyu on their recent publications in Advanced Healthcare Materials. Ting's article explored using injectable, tough alginate cryogels as prophylactic cancer vaccines and Jianyu's article explored using tough composite hydrogels to enable high loading and sustained release...

Read more about Injectable, Tough Alginate Cryogels as Cancer Vaccines and Tough Composite Hydrogels with High Loading and Local Release of Biological Drugs published in Advanced Healthcare Materials