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Sequential modes of crosslinking tune viscoelasticity of cell-instructive hydrogels published in Biomaterials!

January 1, 2019

Congrats to Kyle and team on their recent publication which describes the development of an articial extracellular matrix (ECM) that mimics the fibrillar architecture of natural ECM while supporting independent regulation of its mechanical properties. Check it out here: ... Read more about Sequential modes of crosslinking tune viscoelasticity of cell-instructive hydrogels published in Biomaterials!

Functional muscle recovery with nanoparticle-directed M2 macrophage polarization in mice published in PNAS!

November 1, 2018

Congrats to Theresa on her recent publication which shows that cytokines coupled to gold nanoparticles can be used to direct macrophage polarization following muscle injury in vivo. Check it out here: Functional muscle recovery with nanoparticle-directed M2 macrophage polarization in...

Dr. Nisarg Shah starts faculty position at UCSD

September 2, 2018

Congrats to Nisarg on his new faculty position at the Jacobs School of Engineering at the University of California, San Diego! His presence and scientific contributions will be greatly missed. Check out the cool stuff his lab is working on here: Nanoscale Materials and Cell Engineering Lab Read more about Dr. Nisarg Shah starts faculty position at UCSD

Congratulations to Brian Kwee

August 31, 2018

A big congrats to recent PhD graduate Brian Kwee, who is headed to Dr. Kyung Sung's Lab at the FDA to pursue his postdoctoral studies. His exceptional kindness, positive energy, and dedication will be missed by all. Congrats and best of luck in your new position Brian! Read more about Congratulations to Brian Kwee

Manuscripts published in Biomaterials and PNAS

August 20, 2018

Congrats to recent lab alumnus Max and team on their recent publications in Biomaterials and PNAS, which explore the effects on the microenvironmental material properties on various cells' transcriptional programs. Check them out here:

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Mooney lab summer students present research

August 4, 2018

Congrats to all Mooney lab undergraduates on a productive summer! Great to see such a wide breadth of projects ranging from cell biology to hydrogel mechanics.

Pictured from left: Calvin Marambo, Ege Eskibozkurt, Justine Keth, Luna Nadja Maldonado, Nikko Jeffries, Darnell Cuylear, Soore Oguntuyo, Anna Vaynrub, Evan Thompson

CD4 T-cells regulate angiogenesis and myogenesis published in Biomaterials

June 10, 2018

Congrats to Brian and team on their recent publication which looked at the role of various CD4+ T cell subsets on muscle regeneration. Check it out here: CD4 T-cells regulate angiogenesis and myogenesis!

Mooney Lab seniors honored for outstanding projects

May 15, 2018

Congrats to Mooney Lab senior undergraduates Erica Budina, Kristen Rodrigues, and Jacob Scherba on being honored by SEAS Dean Frank Doyle for the outstanding work on their thesis projects! Well done guys! Click here for the whole story.

Photo credit: SEAS, Harvard University

Biomaterial scaffold-based immunotherapy platforms licensed to Novartis

March 31, 2018

The Wyss Institute at Harvard Universtiy and Dana-Farber Cancer Institute have entered a licensing and collaboration agreement with Novartis to develop our biomaterial systems to delivery next generation immunotherapies. Our approach uses an injectable or implantable biomaterial scaffold that recruits and trains the body's endogenous immune cells to identify and kill a patient's own cancerous cells. A big congratulations to Dave...

A facile approach to enhance antigen response for personalized cancer vaccination published in Nature Materials

March 22, 2018

Congrats to Aileen and team on their recent publication which looked at using polyethyleneimine (PEI) in mesoporous silica rod (MSR) vaccines to enhance antigen immunogenicity. The MSR-PEI vaccine substantially improved therapeutic outcomes in three challenging tumor models while enabling the presentation of large sets of neoantigens and synergizing with checkpoint blockade therapy. Check out their work here: ... Read more about A facile approach to enhance antigen response for personalized cancer vaccination published in Nature Materials

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