The Mooney lab focuses on making therapies more effective and practical. Our research involves exploiting our understanding of cell and molecular biology to design biomaterials that effect and potentiate specific cell functions. The lab members consist of post-doctoral fellows, graduate and undergraduate students, research fellows, and visiting scholars from diverse academic backgrounds. For more information, please visit our publications page, and for any inquiries, please visit our contact page.
Congrats to Brian and team on their recent publication which looked at the role of various CD4+ T cell subsets on muscle regeneration. Check it out here: CD4 T-cells regulate angiogenesis and myogenesis!
Congrats to Mooney Lab senior undergraduates Erica Budina, Kristen Rodrigues, and Jacob Scherba on being honored by SEAS Dean Frank Doyle for the outstanding work on their thesis projects! Well done guys! Click here for the whole story.
Photo credit: SEAS, Harvard University
The Wyss Institute at Harvard Universtiy and Dana-Farber Cancer Institute have entered a licensing and collaboration agreement with Novartis to develop our biomaterial systems to delivery next generation immunotherapies. Our approach uses an injectable or implantable biomaterial scaffold that recruits and trains the body's endogenous immune cells to identify and kill a patient's own cancerous cells. A big congratulations to Dave, Omar, and team! We've still got a lot of work to do.
For more information on our technology, please have a look at the immunotherapy research section.
To view the Novartis press release, click here.
Photo credit: Wyss Institute at Harvard University
Congrats to Ting and Jianyu on their recent publications in Advanced Healthcare Materials. Ting's article explored using injectable, tough alginate cryogels as prophylactic cancer vaccines and Jianyu's article explored using tough composite hydrogels to enable high loading and sustained release of biological payloads. Check out their work here:
Injectable, Tough Alginate Cryogels as Cancer Vaccines
Tough Composite Hydrogels with High Loading and Local Release of Biological Drugs
