Stephen Kennedy
Education
2010 PhD, Electrical Engineering, University of Wisconsin (minor in cell biology)
2006 MS, Electrical Engineering, Univeristy of Wisconsin
2004 BS, Electrical Engineering, University of Wisconsin
Honors and awards
2010 Curtis Carl Johnson Memorial Award for Best Student Paper at the 32nd Annual Meeting of the Bioelectromagnetics Society
2008 – 2010 National Institutes of Health (NIH) Ruth L. Kirschstein National Research Service Award
2008 University of Wisconsin Stem Cell and Regenerative Medicine (SCRM) Cluster Faculty
Interdisciplinary Fellowship in Bioengineering
2008 Gerald Holdridge Award for Teaching Excellence
2008 Second Best Scientific Paper in Student Poster Competition at the 30th Annual Meeting of the Bioelectromagnetics Society
2008 Third Best Scientific Paper in Student Platform Competition at the 30th Annual Meeting of the Bioelectromagnetics Society
2008 Union Radio-Scientifique Internationale (URSI) Travel Award
2006, 2008, 2010 Bioelectromagnetics Society (BEMS) Travel Awards
2006 International Conference on Plasma Science (ICOPS) Travel Award
2005 ElectroMed Travel Award
2003 Tau Beta Pi Engineering Honor Society
1999 – 2004 Deans List (8 semesters)
1999 – 2000 Wisconsin Emerging Scholars Program
Research Focus
My research interests lie in exploiting electromagnetic phenomena for controlling cell behaviors and interactions pertinent to regenerative medicine. This includes (i) direct physical manipulation of cells and cell instructive factors innocuously and at the microenvironmental level and (ii) indirect manipulation of cell behavior through remotely triggered and localized gene and drug delivery.
Publications
Journal articles
1. S. M. Kennedy, K. A. Beres, A. R. Hahn, S. J. Kamin, S. C. Hagness, J. H. Booske, and W. L. Murphy, “A molecularly scaled, electrostimulatory approach for enhanced membrane permeabilization, “Biophys. J. (submitted).
2. Z. Ji*, S. M. Kennedy*, J. H. Booske, and S. C. Hagness, “Spatiotemporal analysis of electropore dynamics and evolution.” Bioelectromagnetics (submitted). * authors contributed equally to this work
3. S. M. Kennedy, Z. Ji, N. B. Rockweiler, A. R. Hahn, J. H. Booske, and S. C. Hagness, “The role of plasmmalemal-cortical anchoring on the stability of transmembrane electropores,” IEEE Trans. Dielectr. Electr. Insul., vol. 16, no. 5, 2009.
4. S. M. Kennedy, Z. Ji, J. C. Hedstrom, J. H. Booske, and S. C. Hagness, “Quantification of electroporative uptake kinetics and electric field heterogeneity effects in cells,” Biophys. J., vol. 95, no. 12, 2008.
5. Z. Ji, S. M. Kennedy, J. H. Booske, S. C. Hagness, “Experimental studies of dynamic cellular membrane response by electroporation of HL-60 cells,” IEEE Trans. Plasma Sci., vol. 34, no. 4, 2006.
Manuscripts in preparation
1. S. M. Kennedy, D. Suarez-Gonzalez, J. P. Coyne, P. Fossum, and W. L. Murphy, “Voltage-controlled deposition of hydroxyapatite on untreated ultra-high molecular weight polyethylene and polyetheretherketone substrates.” (in preparation).
2. K. A. Beres, John H. Booske, S. C. Hagness, and S. M. Kennedy, “The influence of pulsed electric field duration on electroporative thresholds.” (in preparation)
Conference abstracts
1. S. M. Kennedy, K. A. Beres, A. R. Hahn, S. J. Kamin, S. C. Hagness, W. L. Murphy, and J. H. Booske, "Cationic peptide exposure induces electroporation-like molecular uptake in human leukemia cells," IEEE International Symposium on Antennas and Propagation and CNC/USNC/LURSI Radio Science Meeting, Toronto, Ontario, Canada July 2010.
2. S. M. Kennedy, Z. Ji, N. B. Rockweiler, A. R. Hahn, J. H. Booske, and S. C. Hagness, “A locally constrained surface tension model based on cortical anchoring predicts stable electropore development,” 32nd Annual Meeting of The Bioelectromagnetics Society (BEMS), Seoul, Korea, June 2010. Curtis Carl Johnson Memorial Award for best scientific paper presented by a student in the poster competition.
3. S. M. Kennedy, K. A. Beres, A. R. Hahn, S. J. Kamin, S. C. Hagness, W. L. Murphy, and J. H. Booske, "Elicitation of an electroporative response via cationic peptide exposure," 32nd Annual Meeting of The Bioelectromagnetics Society (BEMS), Seoul, Korea, June 2010.
4. K. A. Beres*, S. J. Kamin*, A. R. Hahn*, S. M. Kennedy, J. H. Booske, and S. C .Hagness, "Use of cationic peptide exposure to create an electroporative response in cell membranes," University of Wisconsin Undergraduate Symposium, Madison, WI 2010. Selected for a special session at the Wisconsin State Legislator * authors contributed evenly to this work
5. K. A. Beres*, S. J. Kamin*, A. R. Hahn*, J. C. Headstrom, N. B. Rockweiler, M. Hitchock, S. M. Kennedy, J. H. Booske, and S. C .Hagness, "The influence of electric field exposure time and scale on electrically mediated gene and drug delivery," University of Wisconsin Undergraduate Symposium, Madison, WI 2009. * authors contributed evenly to this work
6. S. Azarin, N. Ferrier, S. M. Kennedy, D. Klingenberg, K. Masters, K. McMahon, J. Russell, and S. C. Hagness, “Work in progress: a first-year introduction-to-engineering course on society’s engineering grand challenges,” 38th ASEE/IEEE Frontiers in Education Conference, Saratoga Springs, NY, October 2008.
7. S. M. Kennedy, Z. Ji, J. C. Hedstrom, J. H. Booske, and S. C. Hagness, “Quantification of electric-field-induced molecular uptake kinetics in human leukemia cells and the regulatory influence of electric field heterogeneity,” XXIXth URSI General Assembly, Chicago, IL, August 2008.
8. S. M. Kennedy, Z. Ji, J. C. Hedstrom, J. H. Booske, and S. C. Hagness, “Real-time quantification of electroporative uptake kinetics and electric field heterogeneity effects in cells,” 30th Annual Bioelectromagnetics Society (BEMS) Meeting, San Diego, CA, June 2008. 3rd place student platform award.
9. S. M. Kennedy, Z. Ji, J. H. Booske, and S. C. Hagness, “Development and characterization of the microcuvette: an exposure device for real-time observation of electroporative molecular uptake,” 30th Annual Bioelectromagnetics Society (BEMS) Meeting, San Diego, CA, June 2008. 2nd place student poster award.
10. S. M. Kennedy, Z. Ji, J. H. Booske, S. C. Hagness, and J. C. Weaver, “Experimental and numerical studies of molecular uptake dynamics in HL60 cells induced by pulsed electric fields,” 16th IEEE International Pulsed Power Conference, June 2007.
11. Z. Ji, S. M. Kennedy, J. H. Booske, S. C. Hagness, “Studies of Persistent Poration Dynamics of Cell Membranes Induced by Electric Pulses,” 28th Annual Bioelectromagnetics Society (BEMS) Meeting, Cancun, Mexico, June 2006.
12. Z Ji, S. M. Kennedy, J. H. Booske, and S. C. Hagness, “Studies of Persistent Poration Dynamics of Cell Membranes Induced by Electric Pulses,” International Conference on Plasma Science (ICOPS), Traverse City, MI, June 2006.
13. Z. Ji. S. M. Kennedy, J. H. Booske, and S. C. Hagness, “Experimental studies of relaxation time constants and membrane memory effects by electroporation,” ElectroMed Conference, Portland, OR, May 2005.
14. N. Redmond, S. M. Kennedy, J. B. Hill, P. Coakley, M. Rose, and P. Mackin, “Potential advantages of 'tight coupling' GPS with inertial navigation systems for in-flight nuclear upset/recovery," Hardened Electronics and Radiation Technology (HEART) Conference, 2003.