Education

Ph.D. in Biotechnology and Bioengineering, EPF Lausanne, Switzerland (2014)

M.Sc. in Biotechnology, ETH Zurich, Switzerland (2008)

B.Sc. in Biochemistry, ETH Zurich, Switzerland (2007)


 

Publications

Lienemann, P. S. , Metzger, S., Kivelio, A., Blanc, A., Papageorgiou, P., Astolfo, A., Pinzer, B. R., Cinelli, P., Weber, F. E., Schibli, R., Béhé, M. & Ehrbar, M. Longitudinal in vivo evaluation of bone regeneration by combined measurement of multi-pinhole SPECT and micro-CT for tissue engineering. Scientific Reports 5, 10238, (2015).

Lienemann, P. S.* , Devaud, Y. R.*, Reuten, R., Simona, B. R., Karlsson, M., Weber, W., Koch, M., Lutolf, M. P., Milleret, V. & Ehrbar, M. Locally controlling mesenchymal stem cell morphogenesis by 3D PDGF-BB gradients towards the establishment of an in vitro perivascular niche. Integrative biology 7, 101-111, (2015). * contributed equally.

Metzger, S., Lienemann, P. S. , Ghayor, C., Weber, W., Martin, I., Weber, F. E. & Ehrbar, M. Modular Poly(ethylene glycol) Matrices for the Controlled 3D-Localized Osteogenic Differentiation of Mesenchymal Stem Cells. Advanced healthcare materials 4 , 550-558, (2015).

Milleret, V., Simona, B. R., Lienemann, P. S. , Voros, J. & Ehrbar, M. Electrochemical control of the enzymatic polymerization of PEG hydrogels: formation of spatially controlled biological microenvironments. Advanced healthcare materials 3, 508-514, (2014).

Mosiewicz, K. A., Kolb, L., van der Vlies, A. J., Martino, M. M., Lienemann, P. S. , Hubbell, J. A., Ehrbar, M. & Lutolf, M. P. In situ cell manipulation through enzymatic hydrogel photopatterning. Nature materials 12, 1072-1078, (2013).

Lienemann, P. S. , Karlsson, M., Sala, A., Wischhusen, H. M., Weber, F. E., Zimmermann, R., Weber, W., Lutolf, M. P. & Ehrbar, M. A versatile approach to engineering biomolecule-presenting cellular microenvironments. Advanced healthcare materials 2, 292-296, (2013).

Karlsson, M., Rebmann, B., Lienemann, P. S. , Sprossmann, N., Ehrbar, M., Radziwill, G. & Weber, W. Pharmacologically controlled protein switch for ON-OFF regulation of growth factor activity. Scientific reports 3, 2716, (2013).

Karlsson, M., Lienemann, P. S. , Sprossmann, N., Heilmann, K., Brummer, T., Lutolf, M. P., Ehrbar, M. & Weber, W. A generic strategy for pharmacological caging of growth factors for tissue engineering. Chemical communications 49, 5927-5929, (2013).

Lienemann, P. S. , Lutolf, M. P. & Ehrbar, M. Biomimetic hydrogels for controlled biomolecule delivery to augment bone regeneration. Advanced drug delivery reviews 64 , 1078-1089, (2012).

Hlushchuk, R., Ehrbar, M., Reichmuth, P., Heinimann, N., Styp-Rekowska, B., Escher, R., Baum, O., Lienemann, P. , Makanya, A., Keshet, E. & Djonov, V. Decrease in VEGF expression induces intussusceptive vascular pruning. Arteriosclerosis, thrombosis, and vascular biology 31, 2836-2844, (2011).

Ehrbar, M., Sala, A., Lienemann, P. , Ranga, A., Mosiewicz, K., Bittermann, A., Rizzi, S. C., Weber, F. E. & Lutolf, M. P. Elucidating the role of matrix stiffness in 3D cell migration and remodeling. Biophysical journal 100 , 284-293, (2011).

Guetg, C., Lienemann, P. , Sirri, V., Grummt, I., Hernandez-Verdun, D., Hottiger, M. O., Fussenegger, M. & Santoro, R. The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats. The EMBO journal 29, 2135-2146, (2010).

Santoro, R., Lienemann, P.  & Fussenegger, M. Epigenetic engineering of ribosomal RNA genes enhances protein production. PloS one 4, e6653, (2009).