Luo Gu

Luo Gu

Postdoctoral Fellow
Luo  Gu

Research Areas:

Cancer immunotherapy

Stem cell mechanotransduction

Nanomaterials for tumor imaging and drug delivery




Chaudhuri O*, Gu L*, Klumpers D, Darnell M, Bencherif SA, Weaver JC, Huebsch N, Lee H, Lippens E, Duda G, Mooney DJ, “Hydrogels with tunable stress relaxation regulate stem cell fate and activity”, Nature Materials 15, 326–334 (2016), *co-first author.

Gu L, Mooney DJ, “Biomaterials and emerging anticancer therapeutics: engineering the microenvironment”, Nature Reviews Cancer 16, 56-66 (2016).

Li W, Lu B, Gu L, Choi Y, Kim J, Mooney DJ, “The effect of surface modification of mesoporous silica micro-rod scaffold on immune cell activation and infiltration”, Biomaterials, 83, 249-256 (2016).

Kennedy S, Hu J, Kearney C, Skaat H, Gu L, Gentili M, Vandenburgh H, Mooney DJ, “Sequential release of nanoparticle payloads from ultrasonically burstable capsules”, Biomaterials, 75, 91-101 (2016).

Chaudhuri O*, Gu L*, Darnell M, Klumpers D, Bencherif SA, Weaver JC, Huebsch N, Mooney DJ, “Substrate stress relaxation regulates cell spreading”, Nature Communications, 6:6365 (2015), *co-first author.

Cezar CA, Kennedy SM, Mehta M, Weaver JC, Gu L, Vandenburgh H, Mooney DJ, “Biphasic ferrogels for triggered drug and cell delivery”, Advanced Healthcare Materials 3, 1869-1876 (2014).

Qin Z, Joo J, Gu L, Sailor MJ, “Size control of porous silicon nanoparticles by electrochemical perforation etching”, Particle & Particle Systems Characterization 31, 252–256 (2014).

Gu L, Hall DJ, Qin Z, Anglin E, Joo J, Mooney DJ, Howell SB, Sailor MJ, “In vivo time-gated fluorescence imaging with biodegradable luminescent porous silicon nanoparticles”, Nature Communications 4:2326 (2013).

Gu L, Fang RH, Sailor MJ, Park JH, “In vivo clearance and toxicity of monodisperse iron oxide nanocrystals”, ACS Nano 6, 4947–4954 (2012).

Gu L, Ruff LE, Qin Z, Corr M, Hedrick SM, Sailor MJ, “Multivalent porous silicon nanoparticles enhance the immune activation potency of agonistic CD40 antibody”, Advanced Materials 24, 3981–3987 (2012).

Singh N, Karambelkar A, Gu L, Lin K, Miller JS, Chen CS, Sailor MJ, Bhatia SN, “Bioresponsive mesoporous silica nanoparticles for triggered drug release”, Journal of the American Chemical Society 133, 19582–19585 (2011).

Xiao L, Gu L, Howell SB, Sailor MJ, “Porous silicon nanoparticle photosensitizers for singlet oxygen and their phototoxicity against cancer cells”, ACS Nano 5, 3651–3659 (2011).

Gu L, Park JH, Duong KH, Ruoslahti E, Sailor MJ, “Magnetic luminescent porous silicon microparticles for localized delivery of molecular drug payloads”, Small 6, 2546–2552 (2010).

Park JH, Gu L, von Maltzahn G, Ruoslahti E, Bhatia SN, Sailor MJ, “Biodegradable luminescent porous silicon nanoparticles for in vivo applications”, Nature Materials 8, 331–336 (2009).

Gu L, Orosco M, Sailor MJ, “Detection of protease activity by FRET using porous silicon as an energy acceptor”, Physica Status Solidi A 206, 1374–1376 (2009).

Contact Information

ESL 415
58 Oxford St.
Cambridge, MA 02138