Dima Shvartsman

Dima Shvartsman

Postdoctoral Fellow
Dima  Shvartsman

Education

 

2008                Ph.D. in Neurobiology

                        Tel Aviv University, Tel Aviv, Israel 

2003                M.Sc. in Neurobiology

                        Tel Aviv University, Tel Aviv, Israel

1998                B.Sc. in Biology

                        Tel Aviv University, Tel Aviv, Israel

 

Research Focus

I am working in the field of regenerative bioengineering at Harvard University School of Engineering and Applied Sciences (SEAS). I am currently a postdoctoral fellow at Prof. Mooney David laboratory, and I focus my research on promoting the vascularization and innervation of skeletal muscle tissues. For that purposes, we employ specifically designed biodegradable polymer scaffolds, supplied with growth factor and adult stem cells. I was awarded an European Molecular Biology Organization (EMBO) Long-Term Fellowship and will continue this project in the future.

Publications

1.        Kim J, Cao L, Shvartsman D, Silva EA, Mooney DJ. Targeted Delivery of Nanoparticles to Ischemic Muscle for Imaging and Therapeutic Angiogenesis. Nano Lett. 2010 Dec 30.

  1.  Huebsch, N., P.R. Arany, A.S. Mao, D. Shvartsman, O.A. Ali, S.A. Bencherif, J. Rivera-Feliciano, and D.J. Mooney. Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate. Nat Mater. 9:518-526.
  2.  Functional muscle regeneration with combined delivery of angiogenesis and myogenesis factors.Borselli C, Storrie H, Benesch-Lee F, Shvartsman D, Cezar C, Lichtman JW, Vandenburgh HH, Mooney DJ .Proc Natl Acad Sci U S A. 2009 Dec 4
  3. Dmitry E. Shvartsman,John C. Donaldson, Begoña Diaz, Orit Gutman, G. Steven Martin, and Yoav I. Henis., “Src kinase activity and SH2 domain regulate the dynamics of Src association with lipid and protein targets.”, Journal of Cell Biology 13 August 2007.
  4. Levkovitz, Y., Ben-Shushan, G., Hershkovitz, A., Isaac, R., Gil-Ad, I., Shvartsman, D., Ronen, D., Weizman, A. and Zick, Y. "Antidepressants induce cellular insulin resistance by activation of IRS-1 kinases.” Molecular and Cellular Neuroscience June 29, 2007. 
  5. Eisenberg S, Shvartsman DE, Ehrlich M, Henis YI., ”Clustering of raft-associated proteins in the external membrane leaflet modulates internal leaflet H-ras diffusion and signaling.”, Molecular Cell Biology. October 26, 2006.
  6. Shvartsman DE, Gutman O, Tietz A, Henis YI. “Cyclodextrins but not compactin inhibit the lateral diffusion of membrane proteins independent of cholesterol.” Traffic, July, 2006.
  7. Dmitry E. Shvartsman, Mariana Kotler, Renee D. Tall, Michael G. Roth and Yoav I. Henis, “Differently-anchored influenza hemagglutinin mutants display distinct interaction dynamics with mutual rafts.” Journal of Cell Biology, Vol.163 (4); pp. 879-88., 2003.
  8. E. Lachmanovich, D. E. Shvartsman,Y. Malka, C. Botvin, Y. I.Henis and A. M.Weiss ., Co-localization analysis of complex formation among membrane proteins by computerized fluorescence microscopy: application to immunofluorescence co-patching studies.”, Journal of Microscopy, Vol. 212, pp122-131,2003.

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