#  Luo Gu 

Postdoctoral Fellow

 

 

 



   ![luogu.jpg](/sites/g/files/omnuum6436/files/styles/hwp_4_5__480x600/public/mooneylab/files/luogu.jpg?itok=D1wh6sVF) 

 



 

 location\_on Current: Assistant Research Professor at John Hopkins University 

 email [luogu \[at\] jhu.edu](<mailto:luogu [at] jhu.edu>) 

 



 

 **Research Areas:**

 Cancer immunotherapy

 Stem cell mechanotransduction

 Nanomaterials for tumor imaging and drug delivery

 **Publications:**

 Chaudhuri O\*, **Gu L**\*, Klumpers D, Darnell M, Bencherif SA, Weaver JC, Huebsch N, Lee H, Lippens E, Duda G, Mooney DJ, “Hydrogels with tunable stress relaxation regulate stem cell fate and activity”, **Nature Materials** 15, 326–334 (2016), \*co-first author.

 **Gu L**, Mooney DJ, “Biomaterials and emerging anticancer therapeutics: engineering the microenvironment”, **Nature Reviews Cancer** 16, 56-66 (2016).

 Li W, Lu B, **Gu L**, Choi Y, Kim J, Mooney DJ, “The effect of surface modification of mesoporous silica micro-rod scaffold on immune cell activation and infiltration”, **Biomaterials**, 83, 249-256 (2016).

 Kennedy S, Hu J, Kearney C, Skaat H, **Gu L**, Gentili M, Vandenburgh H, Mooney DJ, “Sequential release of nanoparticle payloads from ultrasonically burstable capsules”, **Biomaterials**, 75, 91-101 (2016).

 Chaudhuri O\*, **Gu L**\*, Darnell M, Klumpers D, Bencherif SA, Weaver JC, Huebsch N, Mooney DJ, “Substrate stress relaxation regulates cell spreading”, **Nature Communications**, 6:6365 (2015), \*co-first author.

 Cezar CA, Kennedy SM, Mehta M, Weaver JC, **Gu L**, Vandenburgh H, Mooney DJ, “Biphasic ferrogels for triggered drug and cell delivery”, **Advanced Healthcare Materials** 3, 1869-1876 (2014).

 Qin Z, Joo J, **Gu L**, Sailor MJ, “Size control of porous silicon nanoparticles by electrochemical perforation etching”, **Particle &amp; Particle Systems Characterization** 31, 252–256 (2014).

 **Gu L**, Hall DJ, Qin Z, Anglin E, Joo J, Mooney DJ, Howell SB, Sailor MJ, “In vivo time-gated fluorescence imaging with biodegradable luminescent porous silicon nanoparticles”, **Nature Communications** 4:2326 (2013).

 **Gu L**, Fang RH, Sailor MJ, Park JH, “In vivo clearance and toxicity of monodisperse iron oxide nanocrystals”, **ACS Nano** 6, 4947–4954 (2012).

 **Gu L**, Ruff LE, Qin Z, Corr M, Hedrick SM, Sailor MJ, “Multivalent porous silicon nanoparticles enhance the immune activation potency of agonistic CD40 antibody”, **Advanced Materials** 24, 3981–3987 (2012).

 Singh N, Karambelkar A, **Gu L**, Lin K, Miller JS, Chen CS, Sailor MJ, Bhatia SN, “Bioresponsive mesoporous silica nanoparticles for triggered drug release”, **Journal of the American Chemical Society** 133, 19582–19585 (2011).

 Xiao L, **Gu L**, Howell SB, Sailor MJ, “Porous silicon nanoparticle photosensitizers for singlet oxygen and their phototoxicity against cancer cells”, **ACS Nano** 5, 3651–3659 (2011).

 **Gu L**, Park JH, Duong KH, Ruoslahti E, Sailor MJ, “Magnetic luminescent porous silicon microparticles for localized delivery of molecular drug payloads”, **Small** 6, 2546–2552 (2010).

 Park JH, **Gu L**, von Maltzahn G, Ruoslahti E, Bhatia SN, Sailor MJ, “Biodegradable luminescent porous silicon nanoparticles for in vivo applications”, **Nature Materials** 8, 331–336 (2009).

 **Gu L**, Orosco M, Sailor MJ, “Detection of protease activity by FRET using porous silicon as an energy acceptor”, **Physica Status Solidi A** 206, 1374–1376 (2009).



 

 

 





 

 

- ## People
    
     [Alumni](/alumni)