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A biomaterial-based vaccine eliciting durable tumour-specific responses against acute myeloid leukaemia published in Nature Biomedical Engineering

January 4, 2020

Congrats to Nisarg, Alex and team on their recent publication which describes a macroporous-biomaterial vaccine for the treatment of acute myeloid lymphoma (AML). The AML vaccine prevented the engraftment of tumor cells when administered as a prophylactic and in...

Read more about A biomaterial-based vaccine eliciting durable tumour-specific responses against acute myeloid leukaemia published in Nature Biomedical Engineering

Clickable, acid labile immunosuppressive prodrugs for in vivo targeting published in Biomaterial Science

January 1, 2020

Congrats to Hua and team on their recent publication which describes DBCO-modified prodrugs of various immunosuppressive drugs and their targeted conjugation to azido-modified hydrogels via Click chemistry. Placement of these hydrogels in tissues facilitates sustained, local release of drugs and enables repeatable refilling via systemic administration of acid-labile prodrugs after drug...

Read more about Clickable, acid labile immunosuppressive prodrugs for in vivo targeting published in Biomaterial Science